Tip: This is a tough simulation. If you're used to Top Gun, then you're in for a rude awakening. Take the time to work through most, if not all, of the training missions, and perhaps a couple of the simple single missions, before taking on the campaign.
Tip: Choose the right loadout for the mission. If tank busting is the job at hand, don't choose the HARM package. By the same token, if you have been directed to take out the enemy air defense system, don't load up with an unguided Close Air Support (CAS) package.
Tip: In many ways, flying is much like driving a race car: the smoother you are, the better you will be. Treat your Super Hornet gently. Anticipate your next move and flow into it smoothly. Remember, move the control surfaces as slowly as possible while turning, looping, diving, or whatever.
Tip: Your two best friends are airspeed and altitude. Low and slow is bad unless you are either flying inbound to the USS Reagan or trying to move significant amounts of mud. Attempt to keep an altitude advantage on your opponent. You can trade that altitude for speed and--if you come out of the sun--surprise.